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The cover image, in the upper left, shows a control myocyte, with regular sarcomere patterns. In the lower right, a myocyte that has been treated with doxorubicin manifests myofilament disarray. The molecular structure of doxorubicin is also shown. [Confocal images are courtesy of Doug Sawyer and Christian Zuppinger; doxorubicin structure is from the NCBI Cn3D program.]

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