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About the Cover

Cover Figure


This month's cover shows three neuronal cell bodies that together testify to the regenerative ability of the chronically injured spinal cord. One year after injury in the cervical spinal cord (C4), neuronal cell bodies (labeled blue) with severed axons were treated with brain-derived neurotrophic factor. The resulting regeneration of severed axons is evidenced as they make contact with a dye (red) in the distal end of peripheral nerve tissue transplanted into the spinal cord (C3). Where chronically injured cells (i.e., blue) achieve axonal growth through the peripheral nerve graft, they take up the red dye, and thereby appear purple. For details see the Review in this issue by Kwon et al., pages 244­258; the cover image from the authors' laboratory.



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