R E V I E W S:

Michael Overduin, Matthew L. Cheever, and Tatiana G. Kutateladze

Signaling with Phosphoinositides: Better than Binary
Mol. Interv. 2001 1: 150-159. [Abstract] [Full Text] [PDF]  

The enzymatic production and turnover of phosphoinositides provide a dynamic framework for cell signaling. Protein domains that function within this framework are crucial both to our understanding and therapeutic exploitation of cell signals.

Josephine Lai, Michael H. Ossipov, Todd W. Vanderah, T. Philip Malan, Jr., and Frank Porreca

Neuropathic Pain: The Paradox of Dynorphin
Mol. Interv. 2001 1: 160-167. [Abstract] [Full Text] [PDF]  

The link between nerve injury and the development of neuropathic pain has yet to be understood in detail. The implication of dynorphin in the maintenance of neuropathic pain states is gaining attention and may hold the key to effective antinociceptive therapy.

Feng Liu, Kenneth W. Liang, and Leaf Huang

Systemic Administration of Naked DNA: Gene Transfer to Skeletal Muscle
Mol. Interv. 2001 1: 168-172. [Abstract] [Full Text] [PDF]  

Could the intravenous injection of naked DNA be a feasible route to gene therapy? Recent research into this question addresses whether the systemic administration of DNA could provide widespread expression of therapies genes.

D E P A R T M E N T S:

Speaking of Pharmacology:

Editorial

Ray Merenstein, Matthew A. Bowdy, and Mary Woolley

Participating in SCIENCE OUTREACH a civic responsibility for scientists
Mol. Interv. 2001 1: 138-140. [Full Text] [PDF]  

Reflections:

Science in the cultural context

Ryan J. Huxtable

The Mutability of Blue
Mol. Interv. 2001 1: 141-144. [Full Text] [PDF]  

CrossTalk:

Interviews with people in the world of pharmacology

Lee Limbird: "Always thirty seconds away from a changed life"
Mol. Interv. 2001 1: 145-149. [Abstract] [Full Text] [PDF]  

Interviews with people in the world of pharmacologyLee Limbird:"Always thirty seconds away from a changed life."

Beyond the Bench:

Representations of pharmacology and science in the media

Murder on the Syllabus
Mol. Interv. 2001 1: 174-175. [Full Text] [PDF]  

Biology that Asks, "What's Eating You?"
Mol. Interv. 2001 1: 175. [Full Text]  

Net Results:

Sites of interest on the World Wide Web

Sites of interest on the World Wide Web—edited by Rick Neubig
Mol. Interv. 2001 1: 180. [Full Text] [PDF]  

Outliers:

Cartoon

Mol. Interv. 2001 1: 179. [Full Text] [PDF]  

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