HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Weeber, E. J. Articles by Sweatt, J. D. Search for Related Content PubMed PubMed Citation Articles by Weeber, E. J. Articles by Sweatt, J. D.

Molecular Genetics of Human Cognition

Division of Neuroscience, Baylor College of Medicine 1 Baylor Plaza, Houston, TX 77030

An intimate relationship exists between our capacity for learning and memory and the domains of human cognition. This relationship becomes all too clear when a genetic disruption causing the diminished capacity for memory formation results in an individual with a pronounced cognitive deficit. Only recently, through the identification of human genetic mutations that result in mental retardation and learning disorders, have we begun to gain some insight into the genetic and molecular basis of human cognition. The following review describes some of the genetic causes and biochemical consequences of several recently identified genetic disorders that result in a disruption of memory formation and subsequent decline in human cognitive function.

This article has been cited by other articles:

				H. Yang and R. R. Mattingly The Ras-GRF1 Exchange Factor Coordinates Activation of H-Ras and Rac1 to Control Neuronal Morphology Mol. Biol. Cell, May 1, 2006; 17(5): 2177 - 2189. [Abstract] [Full Text] [PDF]

				J. J. Higgins, J. Pucilowska, R. Q. Lombardi, and J. P. Rooney A mutation in a novel ATP-dependent Lon protease gene in a kindred with mild mental retardation Neurology, November 23, 2004; 63(10): 1927 - 1931. [Abstract] [Full Text] [PDF]